Jiawen Li

Jiawen Li is a Ph.D. student in Biomedical Engineering at the Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School (SIGS), Tsinghua University, advised by Prof. Yonghong He and Prof. Tian Guan. He received his Bachelor's degree from Cuiying Honors College, Lanzhou University, and his Master's degree from Open FIESTA at Tsinghua SIGS. He has internships and collaborations with Teksqray (Shenzhen Shengqiang Technology Co, Ltd.), the Research Institute of Tsinghua University in Shenzhen, and the DSAIL lab led by Prof. Jia Li at HKUST(GZ). He also closely collaborates with Prof. Anjia Han and Prof. Huijuan Shi at the First Affiliated Hospital of Sun Yat-sen University.

Jiawen is a recipient of the China National Scholarship for two consecutive years (2025 and 2026), the Second Prize of the China Graduate Mathematical Contest in Modeling, and the Outstanding Undergraduate Thesis Award at Lanzhou University.

His research interests broadly lie in digital medical imaging, computer vision, and deep learning, with a focus on pathology foundation models (self-supervised, weakly supervised pretraining and distillation), gigapixel whole-slide image representation (graph neural networks and multiple instance learning), multimodal learning (vision-language alignment and multimodal LLMs for pathology images), and medical image analysis (3D pathology, polarization imaging, and fundus imaging).

I am currently seeking research positions in digital and computational pathology, medical multimodal learning, or computer vision for healthcare. Feel free to email me.

News

Jul 10, 2026
We present ALICE, a general-purpose pathology foundation model that brings together vision, vision-language, and slide-level experts with multi-stage agglomerative distillation. See Preprint for more details.
Jul 8, 2026
We present StainNet, self-supervised foundation models for immunohistochemistry and special stains, with open-source ViT-Small and ViT-Base versions, which appears at MIDL 2026.
Jun 3, 2026
We present E2E-ViT, an end-to-end method that adapts pre-trained vision transformers to histopathology whole-slide images for survival prediction, which appears at CVPR 2026.
Dec 7, 2025
We present PathTree, which uses diagnostic text to guide hierarchical representation learning for pathological whole-slide image classification, published in Medical Image Analysis.
Nov 19, 2025
We present PathOrchestra, a pathology foundation model spanning 21 tissue types and over 100 clinical-grade tasks, from slide preprocessing to structured report generation, published in npj Digital Medicine. It is also China's first pathology foundation model.
Oct 6, 2024
We present RetMIL, a retentive multiple instance learning model for histopathological whole-slide image classification, which appears at MICCAI 2024.
Jun 17, 2024
We present WiKG, a dynamic graph representation with knowledge-aware attention for histopathology whole-slide image analysis, which appears at CVPR 2024.
Dec 12, 2023
We present DeepTree, a tree-structured model that imitates pathologists' diagnostic strategies for pathological image classification, published in IEEE Transactions on Medical Imaging.

Publications

* equal contribution.  # corresponding author.

Preprints

DeCo-MIL teaser

DeCo-MIL: Debiased Counterfactual Reasoning for Long-Tailed Whole Slide Image Analysis

Xiaoxiao Li*, Xitong Ling*, Jiawen Li*, Weiming Chen, Zhenyang Cai, Xidong Wang, Tian Guan#, Benyou Wang#, Yonghong He#
arXiv:2608.14719, 2026
Paper


Pretraining MIL teaser

Pretraining Multiple Instance Learning Networks with Multi-Teacher Distillation from Pathology Slide Foundation Models

Mingxi Fu*, Jiawen Li*, Renao Yan, Jiali Hu, Qiehe Sun, Tian Guan#, Yonghong He#
arXiv:2607.14703, 2026
Paper Code Weights


ALICE teaser

ALICE: Learning a General-Purpose Pathology Foundation Model from Vision, Vision-Language, and Slide-Level Experts

Jiawen Li*, Tian Guan*, Huijuan Shi*, Xitong Ling, Mingxi Fu, Anjia Han#, Chao He#, Yonghong He#
arXiv:2607.09526, 2026
Paper


Liver pathology resource teaser

A Digital Pathology Resource for Liver Cancer Quantification with Datasets, Benchmarks, and Tools

Ying Xiao*, Shimiao Tang*, Xitong Ling*, Weiming Chen, Jun Wang, Jiawen Li, Huaitian Yuan, Jianghui Yang, Bowen Li, Huan Li, Yiting Meng, Tian Guan, Yonghong He#, Hongfang Yin#
arXiv:2604.22858, 2026
Paper


Token-level representations teaser

To What Extent Do Token-Level Representations from Pathology Foundation Models Improve Dense Prediction?

Weiming Chen*, Xitong Ling*, Xidong Wang, Zhenyang Cai, Yijia Guo, Mingxi Fu, Ziyi Zeng, Minxi Ouyang, Jiawen Li, Yizhi Wang, Tian Guan, Benyou Wang#, Yonghong He#
arXiv:2602.03887, 2026
Paper


HookMIL teaser

HookMIL: Revisiting Context Modeling in Multiple Instance Learning for Computational Pathology

Xitong Ling*, Minxi Ouyang*, Xiaoxiao Li*, Jiawen Li, Ying Chen, Yuxuan Sun, Xinrui Chen, Tian Guan, Xiaoping Liu#, Yonghong He#
arXiv:2512.22188, 2025
Paper


PathFiT teaser

Unlocking adaptive digital pathology through dynamic feature learning

Jiawen Li*, Tian Guan*, Qingxin Xia, Yizhi Wang, Xitong Ling, Jing Li, Qiang Huang, Zihan Wang, Zhiyuan Shen, Yifei Ma, Zimo Zhao, Zhe Lei, Tiandong Chen, Junbo Tan, Xueqian Wang, Xiu-Wu Bian#, Zhe Wang#, Lingchuan Guo#, Chao He#, Yonghong He#
arXiv:2412.20430, 2024
Paper

Conference Papers

Beyond ViT Tokens teaser

Beyond ViT Tokens: Masked-Diffusion Pretrained Convolutional Pathology Foundation Model for Cell-Level Dense Prediction

Weiming Chen*, Xitong Ling*, Zhenyang Cai, Xidong Wang, Jiawen Li, Tian Guan, Benyou Wang#, Yonghong He#
Conference on Neural Information Processing Systems (NeurIPS), 2026
Preprint


E2E-ViT teaser

Turning Pre-Trained Vision Transformers into End-to-End Histopathology Whole Slide Image Models for Survival Prediction

Jiawen Li*, Jiali Hu*, Xitong Ling*, Renao Yan, Yuxuan Chen, Tian Guan#, Yonghong He#
IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2026
Paper Code


StainNet teaser

StainNet: Scaling Self-Supervised Foundation Models on Immunohistochemistry and Special Stains for Computational Pathology

Jiawen Li*, Jiali Hu*, Xitong Ling*, Yongqiang Lv, Yuxuan Chen, Yizhi Wang, Tian Guan#, Yifei Liu#, Yonghong He#
Medical Imaging with Deep Learning (MIDL), 2026
Preprint Code ViT-S ViT-B


MDE-MIL teaser

Multimodal Distillation-Driven Ensemble Learning for Long-Tailed Histopathology Whole Slide Images Analysis

Xitong Ling*, Yifeng Ping*, Jiawen Li*, Jing Peng, Yuxuan Chen, Minxi Ouyang, Yizhi Wang, Yonghong He, Tian Guan#, Xiaoping Liu#, Lianghui Zhu#
IEEE International Symposium on Biomedical Imaging (ISBI), 2026
Preprint


SiMLP teaser

Rethinking Slide-Level Adaptation of Pathology Foundation Models

Jiawen Li*, Jiali Hu*, Qiehe Sun*, Xitong Ling, Yuxuan Chen, Renao Yan, Tian Guan, Anjia Han, Chao He#, Yonghong He#
IEEE International Symposium on Biomedical Imaging (ISBI), 2026
Paper


QPath teaser

QPath: A Question-Aware Multi-Resolution Vision Language Framework for Computational Pathology

Yang Shao, Jiawen Li, Xitong Ling, Yuxuan Chen, Tian Guan#, Yonghong He#
IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2026
Paper


Deformable attention graph teaser

Deformable Attention Graph Representation Learning for Histopathology Whole Slide Image Analysis

Mingxi Fu*, Xitong Ling*, Yuxuan Chen, Jiawen Li, Fanglei Fu, Huaitian Yuan, Tian Guan#, Yonghong He#, Lianghui Zhu#
IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2026
Paper


ProAlign teaser

Cross-Modal Prototype Allocation: Unsupervised Slide Representation Learning via Patch-Text Contrast in Computational Pathology

Yuxuan Chen*, Jiawen Li*, Jiali Hu*, Xitong Ling, Tian Guan#, Anjia Han#, Yonghong He#
IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2025
Paper


FF-to-FFPE teaser

Leveraging Pre-trained Models for FF-to-FFPE Histopathological Image Translation

Qilai Zhang, Jiawen Li, Peiran Liao, Jiali Hu, Tian Guan, Anjia Han#, Yonghong He#
IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2024
Paper Code


RetMIL teaser

RetMIL: Retentive Multiple Instance Learning for Histopathological Whole Slide Image Classification

Hongbo Chu*, Qiehe Sun*, Jiawen Li*, Yuxuan Chen, Lizhong Zhang, Tian Guan, Anjia Han#, Yonghong He#
International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2024
Paper Code


NcIEMIL teaser

NcIEMIL: Rethinking Decoupled Multiple Instance Learning Framework for Histopathological Slide Classification

Qiehe Sun, Doukou Jiang, Jiawen Li, Renao Yan, Yonghong He#, Tian Guan#, Zhiqiang Cheng#
Medical Imaging with Deep Learning (MIDL), 2024
Paper


WiKG teaser

Dynamic Graph Representation with Knowledge-aware Attention for Histopathology Whole Slide Image Analysis

Jiawen Li*, Yuxuan Chen*, Hongbo Chu*, Qiehe Sun, Tian Guan, Anjia Han#, Yonghong He#
IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), 2024
Paper Code


HIQ teaser

HIQ: One-Shot Network Quantization for Histopathological Image Classification

Xinrui Chen, Renao Yan, Yizhi Wang, Jiawen Li, Junru Cheng, Tian Guan#, Yonghong He#
IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2024
Paper


MIL network teaser

Classification of Myopic Maculopathy Images with Self-supervised Driven Multiple Instance Learning Network

Jiawen Li*, Jaehyeon Soon*, Qilai Zhang*, Qifan Zhang, Yonghong He#
International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), 2023
Paper Code Weights

Journal Papers

GASPath teaser

Artificial intelligence-assisted histopathological diagnosis of endocervical gastric-type adenocarcinoma: a multicenter model development and validation study

Jing Yang*, Qiming He*, Jing Peng*, Yizhi Wang, Jiawen Li, Haoxiang Li, Yan Liu, Yuxiang Wang, Ajin Hu, Xitong Ling, Yingwen Zhang, Minxi Ouyang, Xinrui Chen, Lianghui Zhu, Yiqing Liu, Yexing Zhang, Siqi Zeng, Qiang Huang, Zihan Wang, Tian Guan, Yueping Liu#, Ling Chen#, Yan Ding#, Yonghong He#, Congrong Liu#
The Journal of Pathology: Clinical Research (J. Pathol. Clin. Res.), 2026
Paper


DiagR1 teaser

DiagR1: A Vision-Language Model Trained via Reinforcement Learning for Digestive Pathology Diagnosis

Minxi Ouyang*, Lianghui Zhu*, Yaqing Bao*, Qiang Huang, Jingli Ouyang, Tian Guan, Xitong Ling, Jiawen Li, Song Duan, Wenbin Dai, Li Zheng#, Xuemei Zhang#, Yonghong He#
IEEE Journal of Biomedical and Health Informatics (IEEE J. Biomed. Health Inform.), 2026
Paper


CerS-Path teaser

From Generic to Specialized: A Subspecialty Diagnostic System Powered by Self-Supervised Learning for Cervical Histopathology

Yizhi Wang*, Li Chen*, Qiang Huang*, Tian Guan*, Xi Deng, Zhiyuan Shen, Jiawen Li, Xinrui Chen, Bin Hu, Xitong Ling, Taojie Zhu, Zirui Huang, Deshui Yu, Yan Liu, Jiurun Chen, Lianghui Zhu, Qiming He, Yiqing Liu, Diwei Shi, Hanzhong Liu, Junbo Hu, Hongyi Gao, Zhen Song, Xilong Zhao, Chao He#, Ming Zhao#, Yonghong He#
Nature Communications (Nat. Commun.), in press, 2026
Paper


PathTree teaser

Diagnostic text-guided representation learning in hierarchical classification for pathological whole slide image

Jiawen Li*, Qiehe Sun, Renao Yan, Yizhi Wang, Yuqiu Fu, Yani Wei, Tian Guan, Huijuan Shi#, Yonghong He#, Anjia Han#
Medical Image Analysis (Med. Image Anal.), 2025
Paper Code


PathOrchestra teaser

PathOrchestra: A comprehensive foundation model for computational pathology with over 100 diverse clinical-grade tasks

Fang Yan*#, Jianfeng Wu*, Jiawen Li*, Wei Wang*, Yirong Chen, Linda Wei, Jiaxuan Lu, Wen Chen, Zizhao Gao, Jianan Li, Heng Li, Hong Yan, Jiabo Ma, Minda Chen, Yang Lu, Qing Chen, Yizhi Wang, Xitong Ling, Xuenian Wang, Zihan Wang, Qiang Huang, Shengyi Hua, Mianxin Liu, Lei Ma, Tian Shen, Xiaofan Zhang#, Yonghong He#, Hao Chen#, Shaoting Zhang#, Zhe Wang#
NPJ Digital Medicine (NPJ Digit. Med.), 2025
Paper Code Weights


Dynamic hypergraph teaser

Dynamic hypergraph representation for bone metastasis analysis

Yuxuan Chen*, Jiawen Li*, Lianghui Zhu*, Yang Xu, Tian Guan, Huijuan Shi#, Yonghong He#, Anjia Han#
Computer Methods and Programs in Biomedicine (Comput. Methods Programs Biomed.), 2025
Paper


Vectorial adaptive optics teaser

Using optical skyrmions to assess vectorial adaptive optics capabilities in the presence of complex aberrations

Yifei Ma*, Zimo Zhao*, Yuanxing Shen*, Binguo Chen, An Aloysius Wang, Yuxi Cai, Ji Qin, Runchen Zhang, Yunqi Zhang, Jiahe Cui, Bangshan Sun, Jiawen Li, Yuzhu Shi, Liangyu Deng, Honghui He#, Lin Luo#, Yonghong He#, Yun Zhang, Ben Dai, Daniel J. Royston, Steve J. Elston, Stephen M. Morris, Martin J. Booth, Chao He#
Science Advances (Sci. Adv.), 2025
Paper


CAMELYON+ teaser

Comprehensive benchmark dataset for pathological lymph node metastasis in breast cancer sections

Xitong Ling*, Yuanyuan Lei*, Jiawen Li*, Junru Cheng, Wenting Huang, Tian Guan, Jian Guan#, Yonghong He#
Scientific Data (Sci. Data), 2025
Paper Code Camelyon+ Dataset


Retarder array teaser

A reconfigurable arbitrary retarder array as complex structured matter

Chao He*#, Binguo Chen*, Zipei Song*, Zimo Zhao*, Yifei Ma*, Honghui He#, Lin Luo#, Tade Marozsak, An Aloysius Wang, Rui Xu, Peixiang Huang, Jiawen Li, Xuke Qiu, Yunqi Zhang, Bangshan Sun, Jiahe Cui, Yuxi Cai, Yun Zhang, Andong Wang, Mohan Wang, Patrick Salter, Julian AJ Fells, Ben Dai, Shaoxiong Liu, Limei Guo, Yonghong He, Hui Ma, Daniel J. Royston, Steve J. Elston, Qiwen Zhan, Chengwei Qiu, Stephen M. Morris, Martin J. Booth, Andrew Forbes
Nature Communications (Nat. Commun.), 2025
Paper


Cervical lymph node teaser

A deep learning method for predicting the origins of cervical lymph node metastatic cancer on digital pathological images

Runliang Zheng*, Xuenian Wang*, Lianghui Zhu, Renao Yan, Jiawen Li, Yani Wei, Fenfen Zhang, Hong Du, Linlang Guo, Yonghong He#, Huijuan Shi#, Anjia Han#
iScience, 2024
Paper


DeepTree teaser

DeepTree: Pathological image classification through imitating tree-like strategies of pathologists

Jiawen Li*, Junru Cheng*, Lingqin Meng, Hui Yan, Yonghong He, Huijuan Shi#, Tian Guan#, Anjia Han#
IEEE Transactions on Medical Imaging (IEEE Trans. Med. Imaging), 2024
Paper Code

Education

Tsinghua University

Aug 2024 - Present
Ph.D. student in Biomedical Engineering
Tsinghua Shenzhen International Graduate School, Institute of Biopharmaceutical and Health Engineering (iBHE)


Tsinghua University

Sep 2021 - June 2024
M.S. in Biomedical Engineering
Tsinghua Shenzhen International Graduate School, Open FIESTA, BIO³ (Biology–Nanobiology–Bioinformatics)


Lanzhou University

Sep 2017 - July 2021
B.S. in Mathematics and Applied Mathematics
Cuiying Honors College, Mathematics Experimental Class, Top-Notch Student Training Program in Basic Disciplines (Mount Everest Plan)

Experience

Internships

Reviewing

  • Conference Reviewer: CVPR、NeurIPS、ICLR、AAAI、ACM MM、MICCAI
  • Journal Reviewer: IEEE Transactions on Medical Imaging (TMI)、Pattern Recognition (PR)、Expert Systems with Applications (ESWA)

Awards

  • 2026, China National Scholarship (国家奖学金)
  • 2025, China National Scholarship (国家奖学金)
  • 2023, Institute-Level Second-Class Scholarship, Tsinghua University
  • 2022, Second Prize, 19th China Graduate Mathematical Contest in Modeling
  • 2021, Outstanding Undergraduate Thesis, Lanzhou University
  • 2018, Provincial Third Prize in Mathematics, 10th Chinese Mathematics Competitions
  • 2017, University Third-Class Scholarship, Lanzhou University

Teaching

Teaching Assistant

  • Interdisciplinary Innovation Practice Course - Digital Healthcare (数字医疗), SIGS, THU, 2026 Spring
  • Artificial Intelligence and Innovative Design Capstone Project (人工智能与创新设计), SIGS, THU, 2025 Autumn
  • Interdisciplinary Innovation Practice Course - Digital Healthcare (数字医疗), SIGS, THU, 2025 Spring
  • Advanced Numerical Analysis (高等数值分析), SIGS, THU, 2024 Autumn